94427-39-1

Upstream product

• 94427-38-0 1-acetyl-4-(3',4'-dimethoxyphenyl)-1,2,3,6-tetrahydropyridine 
• 73390-11-1 4-piperidinone monohydrate 
• 2859-78-1 4-Bromoveratrole 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 90684-19-8 4-(3'-methoxy-4'-hydroxyphenyl)-1,2,3,6-tetrahydropyridine 
• 94427-33-5 1-acetyl-4-(3'-methoxy-4'-acetoxyphenyl)-1,2,3,6-tetrahydropyridine 
• 94427-34-6 1-acetyl-4-(3'-methoxy-4'-hydroxyphenyl)-1,2,3,6-tetrahydropyridine 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 39795-63-6 4-(3,4-dimethoxyphenyl)pyridine 

Relevant academic research and scientific papers

SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION

The present invention covers aminoquinolone compounds of general formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8 and n are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and/or prophylaxis of diseases, in particular of diacylglycerol kinase alpha regulated disorders, as a sole agent or in combination with other active ingredients.

Synthesis and Dihydropteridine Reductase Inhibitory Effects of Potential Metabolites of the Neurotoxin 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a nigrostriatal neurotoxin which can cause irreversible parkinsonism in humans and primates by selective destruction of neurons in the substantia nigra.It is possible that MPTP could be metabolized by