944280-13-1

Usage

Physical state

Clear liquid

Uses

Reagent in organic synthesis, pharmaceutical research, building block in the synthesis of various pharmaceuticals and fine chemicals

Properties

Mild sedative and analgesic effects, potential antifungal properties, used as an intermediate in the synthesis of organic compounds

Derivative of

2-methylpropan-1-ol

Group attached

3-iodo-4-methoxyphenyl group on the carbon atom

Significance

Diverse range of applications and potential pharmacological properties in medicinal and chemical research.

Upstream product

• 32454-29-8 2-(4-methoxy-phenyl)-2-methyl-propan-1-ol 

Downstream Products

• 944280-14-2 2-[4-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxoborolan-2-yl)phenyl]-2-methylpropan-1-ol 

Relevant academic research and scientific papers

CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS

Compounds of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), A1 is a cyclic group, and B is a cyclic group which is attached to the heterocyclic ring directly or through a methylene group.

CETP INHIBITORS

Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B is a cyclic group other than phenyl, and B has a cyclic substituent at a position that is ortho to the position at which B is connected to the remainder of the structure of Formula (I). The 5-membered ring of Formula (I) has a second cyclic substituent in addition to B.