944389-34-8

Basic information

• Product Name: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)but-3-yl-2-ol
• Synonyms: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)but-3-yl-2-ol
• CAS NO: 944389-34-8
• Molecular Weight: 422.478
• Mol File: 944389-34-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)but-3-yl-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)but-3-yl-2-ol(944389-34-8)
• EPA Substance Registry System: 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)but-3-yl-2-ol(944389-34-8)

Safety Data

• Hazardous Substances Data: 944389-34-8(Hazardous Substances Data)

Upstream product

• 634153-28-9 4-[(3-methoxy)-2-(methoxymethoxy)phenyl]-2-methylbutyn-3-yn-2-ol 
• 165071-94-3 1-iodo-3-methoxy-2-(methoxymethoxy)benzene 
• 90-05-1 2-methoxy-phenol 
• 73220-26-5 1-methoxy-2-(methoxymethoxy)benzene 
• 3697-96-9 1-allyl-2-naphthol 
• 944389-24-6 3-[2-(methoxymethoxy)naphthalen-1-yl]-1,2-propanediol 
• 944389-23-5 1-allyl-2-methoxymethoxy-naphthalene 
• 944389-25-7 2-(2-methoxymethoxy-naphthalen-1-yl)acetaldehyde 
• 634153-25-6 1-ethynyl-3-metyhoxy-2-(2-methoxymethoxy)benzene 

Downstream Products

• 944389-36-0 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)butan-2-ol 
• 913003-75-5 4-(3-methoxy-2-(methoxymethoxy)phenyl)-1-(2-methoxymethoxy-naphthalen-1-yl)butan-2-one 

Relevant articles and documents

Synthesis of aromatic spiroacetals related to γ-rubromycin based on a 3H-spiro[1-benzofuran-2,2′-chromane] skeleton

The synthesis of a series of aromatic 5,6-benzannelated and naphthyl-benzannelated spiroacetals related to the spiroacetal unit present in the quinonoid antibiotic γ-rubromycin is reported. The key steps include the use of Sonogashira coupling to construct an aryl acetylene that is coupled to an aryl aldehyde forming a propargyl alcohol intermediate. Hydrogenation of the resultant alkynol followed by oxidation produces a masked dihydroxyketone that upon treatment with silica-supported sodium hydrogen sulfate undergoes concomitant deprotection and cyclisation to afford the desired fused aromatic spiroacetal.