944449-32-5Relevant academic research and scientific papers
Ti-catalyzed regioselective ring-opening alkynylation of epoxides with haloalkynes
Zhang, Di,Li, Hao,Yi, Dong,Tu, Shijing,Qi, Zhongyu,Wei, Siping,Fu, Qiang,Fu, Haiyan,Du, Xi
supporting information, (2021/11/01)
Ti-catalyzed ring-opening alkynylation of epoxides with haloalkynes has been achieved, allowing an efficient and regioselective entry to various propargylic alcohols in moderate to good yields. The developed protocol features extremely mild reaction conditions, broad substrate scope, varied functional group compatibility, and chemospecificity in the rearrangements of epoxides to aldehydes.
Cu(I)-catalyzed oxidative cyclization of enynamides: Regioselective access to cyclopentadiene frameworks and 2-aminofurans
Shen, Wen-Bo,Tang, Xiang-Ting,Zhang, Ting-Ting,Liu, Si-Yu,He, Jiang-Man,Su, Tong-Fu
supporting information, p. 6799 - 6804 (2020/09/15)
An efficient Cu(I)-catalyzed oxidative cyclization of alkynyl-tethered enynamides for the construction of fused bicyclic cyclopentadiene derivatives is disclosed. The cascade proceeds through alkyne oxidation, carbene/alkyne metathesis, and formal (3 + 2)
A practical synthesis of benzothiophenes via visible-light-promoted cyclization of disulfides and alkynes
Ye, Lin-Miao,Qian, Lu,Chen, Yan-Yan,Zhang, Xue-Jing,Yan, Ming
supporting information, p. 550 - 554 (2017/01/25)
Visible-light-promoted intermolecular radical cyclization of disulfides and alkynes has been developed. Benzothiophenes bearing ester, ketone, aldehyde and aryl substituents were synthesized in good yields. The reaction was carried out in the absence of t
Rhodium-catalyzed carbonylation of cyclopropyl substituted propargyl esters: A tandem 1,3-acyloxy migration [5 + 1] cycloaddition
Shu, Dongxu,Li, Xiaoxun,Zhang, Min,Robichaux, Patrick J.,Guzei, Ilia A.,Tang, Weiping
experimental part, p. 6463 - 6472 (2012/09/22)
We have developed two different types of tandem reactions for the synthesis of highly functionalized cyclohexenones from cyclopropyl substituted propargyl esters. Both reactions were initiated by rhodium-catalyzed Saucy-Marbet 1,3-acyloxy migration. The r
Highly efficient synthesis of tri- and tetrasubstituted conjugated enynes from Bronsted acid catalyzed alkoxylation of 1-cyclopropylprop-2-yn-1-ols with alcohols
Mothe, Srinivasa Reddy,Chan, Philip Wai Hong
supporting information; experimental part, p. 5887 - 5893 (2009/12/24)
(Chemical Equation Presented) A highly efficient triflic acid catalyzed ring opening of a wide variety of 1-cyclopropyl-2-propyn-1-ols with alcohols as an efficient synthetic route to conjugated enynes is reported herein. The reaction was operationally st
