944458-48-4Relevant academic research and scientific papers
PROCESS FOR PRODUCTION OF SUBSTITUTED BENZENE
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Page/Page column 31, (2010/07/08)
Disclosed is a process for production of a substituted benzene, which comprises intramolecularly and/or intermolecularly trimerizing a triple bond in an alkyne in the presence of a transition metal catalyst to yield a substituted benzene compound. In the process, the transition metal catalyst is prepared from an iminomethylpyridine represented by the formula (1) or (2), a transition metal salt or a hydrate thereof, and a reducing agent in a reaction system and is used to perform the trimerization. The process can be used in any one of the intramolecular cyclization of a triyne compound, the cyclization of a diyne compound or an alkyne compound and the intermolecular cyclization of three molecules of an alkyne compound, is excellent in economic effectiveness and operability, and is practically advantageous. wherein R1 and R3 independently represent a linear or cyclic C1-C20 aliphatic hydrocarbon group or the like; R2 represents a hydrogen atom or the like; X represents a hydrogen atom, O or the like; and Y represents O, S or the like.
Synthesis of substituted anthracenes, pentaphenes and trinaphthylenes via alkyne-cyclotrimerization reaction
Saino, Naoko,Kawaji, Tsuyoshi,Ito, Taichi,Matsushita, Yuko,Okamoto, Sentaro
scheme or table, p. 1313 - 1316 (2010/04/29)
The [2+2+2] cycloaddition reaction of 1,6-diynes 3 with 4-aryl-2-butyn-1-ols 4 and the following oxidation of the resulting benzylic alcohols to the aldehydes 1 and then treatment with an acid catalyst provided annulated anthracenes 2 in good yields.
