944686-02-6Relevant academic research and scientific papers
A highly efficient route to C-3 alkyl-substituted indoles via a metal-free transfer hydrogenation
Chen, Cai,Feng, Huan-Xi,Li, Zhi-Long,Cai, Pin-Wen,Liu, Yan-Kai,Shan, Lian-Hai,Zhou, Xian-Li
supporting information, p. 3774 - 3776 (2014/07/07)
A highly efficient route to C-3 alkyl-substituted indoles via completely metal-free catalytic transfer hydrogenation of 3-indolemethanols was developed. This process proceeds via vinylogous iminium intermediates formed in situ in the presence of Br?nsted
The direct asymmetric alkylation of α-amino aldehydes with 3-indolylmethanols by enamine catalysis
Guo, Zhi-Lei,Xue, Jia-Hui,Fu, Li-Na,Zhang, Shun-En,Guo, Qi-Xiang
supporting information, p. 6472 - 6475 (2015/01/16)
This work describes an efficient α-alkylation reaction of α-amino aldehydes with 3-indolylmethanols. In the promotion of catalyst 3f, the target products were obtained in high yields (up to 99%), good diastereoselectivities (up to 88:12), and excellent en
Highly enantioselective alkylation reaction of enamides by bronsted-acid catalysis
Guo, Qi-Xiang,Peng, Yun-Gul,Zhang, Jin-Wei,Song, Liu,Feng, Zhang,Gong, Liu-Zhu
supporting information; experimental part, p. 4620 - 4623 (2009/12/09)
The H8-BINOL-derived, phosphoric acid catalyzed, highly enatioselective alkylation reaction of enamides with Indoiyl alcohols has been described. A phosphoric acid derived from H8-BINOL enabled an asymmetric α-alkylation of enamides with indoiy
