944709-63-1

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-2,3-Dihydrobenzofuran-3-amine Hydrochloride is used as a pharmaceutical intermediate for its potential to contribute to the development of drugs with various therapeutic applications. Its presence in a hydrochloride salt form may facilitate its use in drug formulations due to improved water solubility.
Used in Research and Development:
In the field of medicinal chemistry, 6-Bromo-2,3-Dihydrobenzofuran-3-amine Hydrochloride serves as a key compound for research into its biological activities. It is utilized in studies aimed at understanding its anti-inflammatory, anti-microbial, and anti-cancer properties, which could lead to the discovery of new therapeutic agents.
Used in Drug Synthesis:
6-Bromo-2,3-Dihydrobenzofuran-3-amine Hydrochloride is used as a building block in the synthesis of more complex drug molecules. Its unique structure allows for the creation of novel compounds with potential therapeutic benefits, which can be further optimized through chemical modifications.

InChI:InChI=1/C8H8BrNO.ClH/c9-5-1-2-6-7(10)4-11-8(6)3-5;/h1-3,7H,4,10H2;1H

Upstream product

• 22532-62-3 4-bromosalicylaldehyde 
• 1392072-52-4 (rac)-6-bromo-2,3-dihydrobenzofuran-3-ol 
• 1392072-56-8 (rac)-3-azido-6-bromo-2,3-dihydrobenzofuran 

Relevant academic research and scientific papers

ALPHA, BETA-UNSATURATED AMIDE COMPOUND

An object of the present invention is to provide an α,β-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like. The α,β-unsaturated amide compound represented by the following formula (I) or a pharmaceutically acceptable salt or the like thereof has anticancer activity and the like: [wherein, "A" represents optionally substituted heterocyclic diyl, R1 represents hydrogen atom or optionally substituted lower alkyl, R2 represents optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted aliphatic heterocyclic group or optionally substituted aromatic heterocyclic group, X represents -O-, -S-, -SO2-, -NRX1- (wherein, RX1 represents hydrogen atom or lower alkyl), -CHRX2- (wherein, RX2 represents hydrogen atom or hydroxy), -CH=CH-, -CO- or -NH-CO-, and n1 and n2 are the same or different, and each represents 0 or 1].

DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS

Provided are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, Z, B, R1, R2, R3, G1, G2, and G3 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof Also provided are methods of using a compound of Formula (I), or a pharmaceutically acceptable salt, thereof for use in methods of treatment heart diseases through cardiac sarcomere inhibtion.

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general Formula (I), wherein R1, R2, R3, R4 R5, R6, R7, R8 R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.