944729-58-2Relevant academic research and scientific papers
Design and synthesis of chiral N-chloroimidodicarbonates: Application to asymmetric chlorination of silyl enol ethers
Hajra, Saumen,Bhowmick, Manishabrata,Maji, Biswajit,Sinha, Debarshi
, p. 4872 - 4876 (2007)
(Chemical Equation Presented) New chiral N-chloroimidodicarbonates, which function as efficient chiral chlorinating agents, were designed and synthesized. Among these, C2-symmetric (1R,2S,5R)-(-)-menthyl-N- chloroimidodicarbonate 2a provided moderate to good enantioselectivity (up to 40%) for the chlorination of silyl enol ethers to afford α-chloroketones only in the presence of a suitable Lewis acid such as Sm(OTf)3.
