944733-25-9

Upstream product

• 139903-48-3 phenyl-2,3,4,6-tetra-O-benzyl-1-seleno-β-D-galactopyrannoside 
• 75-61-6 dibromodifluoromethane 
• 138511-92-9 1,5-anhydro-2,3,4,6-tetra-O-benzyl-D-lyxo-hex-1-enitol 

Downstream Products

• 1308272-25-4 C₃₉H₄₆BrF₂NO₉ 
• 1467598-35-1 (2S,3R,4S,5R,6R)-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)-2-(bromodifluoromethyl)tetrahydro-2H-pyran-3-yl (2R,3S,4R)-3,4-bis(benzyloxy)-2-((tertbutoxycarbonyl)amino)nonanoate 
• 1308272-18-5 bromo-difluoro-(3,4,6-tri-O-benzyl-α-D-galactopyranosyl)methane 
• 1308272-30-1 C₃₀H₃₁BrF₂O₆ 
• 1308272-27-6 2,3,4-tri-N,O,O-acetyl-1,1-difluoro-1-(2-O-acetyl-3,4,6-tri-O-benzyl-α-D-galactopyranosyl)-3-amino-4-hydroxy-butan-2-ol 
• 1308272-24-3 C₃₉H₄₉F₂NO₉ 
• 1308272-26-5 C₃₉H₄₇F₂NO₉ 
• 1308272-22-1 C₃₀H₃₂F₂O₆ 

Relevant academic research and scientific papers

Addition of difluoromethyl radicals to glycals: A new route to α-CF2-D-glycosides

The synthesis of synthetically useful α-CF2 glycosides by radical addition of ethyl bromodifluoroacetate onto 2-benzyloxyglycals Is described. The methodology provides an access to α-O-glycoside mimics and, potentially, to valuable α-O-glycocon

Addition of electrophilic radicals to 2-benzyloxyglycals: Synthesis and functionalization of fluorinated α-C-glycosides and derivatives

A new method for the synthesis of fluorinated α-C-glycosides is described. The reactions between highly electrophilic radicals (fluorinated or unfluorinated) and a 2-benzyloxyglucal or galactal provide 2-keto-D-arabino- or 2-keto-D-lyxo-hexopyranosides th

Straightforward preparation of functionalized α-CF 2-galactosides through an oxygen to carbon acyl migration

A privileged Glycon! A radical-addition Meerwein-Ponndorf-Verley (MPV) reduction sequence provides access to functionalized α-CF 2-galactosides (see scheme). Introduction of a CF2Br group in the pseudo-anomeric position aided the transfer of an aglycon chain from O-2 to C-1′ through an intramolecular addition-reduction sequence, which involved a Br-Li exchange. This methodology gives access to a wide range of fluorinated C-glycosidic analogues of glycoconjugates.