944788-58-3

Upstream product

• 16160-76-2 1-isopropyl-4-oxo-piperidine-3-carboxylic acid ethyl ester; hydrochloride 
• 618-39-3 benzamidin 

Downstream Products

• 944788-62-9 6-acetyl-8-isopropyl-2-phenyl-5,8,9,10-tetrahydropyrimido[4,5-d]azocin-4(3H)-one 
• 944777-24-6 methyl 8-isopropyl-4-oxo-2-phenyl-3,4,5,8,9,10-hexahydropyrimido[4,5-d]azocine-6-carboxylate 
• 1325234-35-2 dimethyl 8-isopropyl-4-oxo-2-phenyl-3,4,5,8,9,10-hexahydropyrimido[4,5-d]azocine-6,7-dicarboxylate 
• 1325234-37-4 dimethyl (2E)-2-(isopropyl{2-[5-(methoxymethyl)-6-oxo-2-phenyl-1,6-dihydropyrimidin-4-yl]ethyl}amino)but-2-enedioate 

Relevant academic research and scientific papers

2-Alkyl-4-oxohexahydropyrimido[4,5-d]- and -[5,4-d]azocines

It has been established that 2-R-4-oxotetrahydropyrido[4,3-d]pyrimidines, under the action of activated alkynes in methanol, form a mixture of 2-R-4-oxohexahydropyrimido[4,5-d]azocines and products of decomposition of the tetrahydropyridine ring, the 2-R-5-methoxymethyl-4-oxo-6-vinylaminoethyl- pyrimidines. Tetrahydropyrido[3,4-d]pyrimidine, isomeric at the junction of the pyrimidine and tetrahydropyridine rings, forms only the corresponding pyrimido[5,4-d]azocine, the product of expansion, under the action of methyl propiolate.