944805-22-5 Usage
Uses
Used in Pharmaceutical Research and Organic Synthesis:
5-bromo-4-fluoro-2-nitrophenol is utilized as a reagent in pharmaceutical research and organic synthesis due to its strong electron-withdrawing properties. Its presence in the phenol ring allows for the creation of new compounds with potential therapeutic applications, making it an important intermediate in the development of novel pharmaceuticals.
Used in Agrochemical Production:
5-bromo-4-fluoro-2-nitrophenol also serves as an intermediate in the production of various agrochemicals. Its unique structure contributes to the development of new agrochemicals that can be used in agriculture to protect crops and enhance yields.
Used in Dye and Pigment Manufacturing:
5-bromo-4-fluoro-2-nitrophenol is used as a precursor in the manufacturing of dyes and pigments. Its chemical properties allow for the creation of a range of colors and hues, making it a valuable component in the production of various dyes and pigments for different industries.
Used in Specialty Chemicals Production:
Furthermore, 5-bromo-4-fluoro-2-nitrophenol is employed in the production of specialty chemicals. Its unique structure and properties make it suitable for use in the synthesis of a variety of specialty chemicals that have specific applications in different industries.
It is crucial to handle 5-bromo-4-fluoro-2-nitrophenol with care due to its potential toxicity and environmental impact. Proper safety measures should be taken to minimize any risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 944805-22-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,8,0 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 944805-22:
(8*9)+(7*4)+(6*4)+(5*8)+(4*0)+(3*5)+(2*2)+(1*2)=185
185 % 10 = 5
So 944805-22-5 is a valid CAS Registry Number.
944805-22-5Relevant academic research and scientific papers
Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model
Pero, Joseph E.,Rossi, Michael A.,Lehman, Hannah D.G.F.,Kelly, Michael J.,Mulhearn, James J.,Wolkenberg, Scott E.,Cato, Matthew J.,Clements, Michelle K.,Daley, Christopher J.,Filzen, Tracey,Finger, Eleftheria N.,Gregan, Yun,Henze, Darrell A.,Jovanovska, Aneta,Klein, Rebecca,Kraus, Richard L.,Li, Yuxing,Liang, Annie,Majercak, John M.,Panigel, Jacqueline,Urban, Mark O.,Wang, Jixin,Wang, Ying-Hong,Houghton, Andrea K.,Layton, Mark E.
supporting information, p. 2683 - 2688 (2017/05/29)
Studies on human genetics have suggested that inhibitors of the Nav1.7 voltage-gated sodium channel hold considerable promise as therapies for the treatment of chronic pain syndromes. Herein, we report novel, peripherally-restricted benzoxazoli
BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS
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Paragraph 0201, (2014/05/24)
Disclosed are compounds of Formula A: Formula A, or a salt thereof, wherein "Het", Ra, and Rb are defined herein, which have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating neuropathic pain disorders using the same.
Thiazole compounds and methods of use
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Page/Page column 80, (2008/06/13)
The invention relates to thiazole compounds of Formula I and Formula II and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.
