94483-64-4Relevant academic research and scientific papers
Convergent synthesis of tetra- and penta-saccharide fragments of dimeric Lewis X
Forman, Adam,Hendel, Jenifer,Auzanneau, France-Isabelle
, (2019/07/04)
The convergent synthesis of tetra- and penta-saccharide fragments of the TACA dimeric Lex is described. The synthetic strategy relied on the preparation of a protected GlcNTCA-(1,3)-Gal-(1,4)-GlcNAc trisaccharide diol free at O-3 of both glucos
N-ACETYLGLUCOSAMINE DERIVATIVES AND USE THEREOF
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Page/Page column 13, (2010/02/12)
The present invention relates to An N-acetylglucosamine derivative represented by the following formula (1), and a hyaluronic acid production promoting agent containing the same and a skin external preparation containing the same: wherein R1 is a hydrogen atom or an alkyl group having 2 to 18 carbon atoms; R2, R3, and R4 are hydrogen atoms or acyl groups having 2 to 18 carbon atoms and may be all the same or different from others; the steric structure at position 1 may be α or β; provided that R1, R2, R3, and R4 must not be all hydrogen atoms. It is intended to provide an easily available hyaluronic acid production promoting agent and a skin external preparation whereby the production of hyaluronic acid can be promoted in the skin and thus the skin can be maintained in a vital and moist state so that it is expected that the human skin can be prevented from age.
A spacer-modified disaccharide as a photoaffinity reagent for the acceptor-binding area of bovine (1->4)-β-D-galactosyltransferase: comparison of its acceptor properties with those of other 2-acetamido-2-deoxy-β-D-glucopyranosides
Ats, Sandor-Csaba,Lehmann, Jochen,Petry, Stefan
, p. 125 - 139 (2007/10/02)
The spacer-modified disaccharide 1,10-di-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-azi-1,10-decanediol (10) that mimics the biantennary core heptasaccharide of N-glycoproteins has been synthesised.Compound 10 is an excellent acceptor in galactosyltransferase-catalysed galactosylation by UDP-galactose, is superior (7-8 fold) to analogues that have only one GlcNAc unit, and is an efficient photoaffinity reagent for galactosyltransferase.In the presence of UDP-Gal, no photoaffinity labelling by 10 takes place, which agrees with the mechanism of galactosyltransferase action.
