944892-25-5 Usage
Uses
Used in Pharmaceutical Industry:
2-butyl-1,3,4-oxadiazole is used as a chemical intermediate for the synthesis of various pharmaceuticals, leveraging its unique structure to contribute to the development of new drugs.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 2-butyl-1,3,4-oxadiazole serves as a chemical intermediate, aiding in the production of compounds that have potential applications in agriculture, such as pesticides or herbicides.
Used in Organic Compounds Synthesis:
2-butyl-1,3,4-oxadiazole is utilized as a building block in the synthesis of other organic compounds, given its reactive functional groups and structural properties that can be incorporated into more complex molecules.
Used in Biological and Pharmacological Research:
2-butyl-1,3,4-oxadiazole is studied for its potential biological and pharmacological activities, such as antimicrobial, antiviral, and antitumor properties, serving as a subject of research to explore its therapeutic potential.
While the compound's applications are diverse, further research is necessary to fully understand and harness the potential of 2-butyl-1,3,4-oxadiazole across various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 944892-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,8,9 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 944892-25:
(8*9)+(7*4)+(6*4)+(5*8)+(4*9)+(3*2)+(2*2)+(1*5)=215
215 % 10 = 5
So 944892-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H10N2O/c1-2-3-4-6-8-7-5-9-6/h5H,2-4H2,1H3
944892-25-5Relevant academic research and scientific papers
Development of orally active nonpeptidic inhibitors of human neutrophil elastase
Ohmoto,Yamamoto,Okuma,Horiuchi,Imanishi,Odagaki,Kawabata,Sekioka,Hirota,Matsuoka,Nakai,Toda,Cheronis,Spruce,Gyorkos,Wieczorek
, p. 1268 - 1285 (2007/10/03)
5-Amino-2-phenylpyrimidin-6-ones, some of their desamino derivatives, and miscellaneous derivatives were synthesized and biologically evaluated on both in vitro activity and oral activity in an acute hemorrhagic assay. These compounds contained an α-keto-1,3,4-oxadiazole moiety to bind covalently to the Ser-195 hydroxy group of human neutrophil elastase (HNE). Among those tested, compounds 11a-c,e,i-l(F), 11d,e,k(H), 21d,e,k(F), and 21d,e(H) showed a good oral profile. RS-Mixture 3(H) was selected for clinical evaluation based on its oral potency, duration of action, enzyme selectivity, safety profile, and ease of synthesis. Structure -activity relationships (SARs) are discussed.
