944901-09-1 Usage
Uses
Used in Pharmaceutical Industry:
4-Cyano-1H-pyrrole-2-carboxylic acid ethyl ester is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs. Its presence in the synthesis process aids in the creation of compounds with therapeutic effects, enhancing drug discovery and innovation.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Cyano-1H-pyrrole-2-carboxylic acid ethyl ester is utilized as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals that are vital for crop protection and yield enhancement.
Used in Organic Synthesis:
As a versatile building block in organic synthesis, 4-Cyano-1H-pyrrole-2-carboxylic acid ethyl ester is employed in the creation of a wide range of organic compounds for various applications, including the development of new materials and the improvement of existing ones.
It is important to handle and store 4-Cyano-1H-pyrrole-2-carboxylic acid ethyl ester with care due to its potential health and environmental hazards, ensuring safe practices in laboratories and manufacturing facilities.
Check Digit Verification of cas no
The CAS Registry Mumber 944901-09-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 944901-09:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*1)+(2*0)+(1*9)=181
181 % 10 = 1
So 944901-09-1 is a valid CAS Registry Number.
944901-09-1Relevant articles and documents
Synthesis of isoquinolinone-based tricycles as novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors
Chen, Jianyang,Peng, Haixia,He, Jinxue,Huan, Xiajuan,Miao, Zehong,Yang, Chunhao
, p. 2669 - 2673 (2014/06/09)
The isoquinolinone-based tricyclic compounds were designed and synthesized. Preliminary biological study of these compounds provided potent compounds 17a, 33b, 33c, 33d, and 33g with low nanomolar IC50s against PARP-1 enzyme.
A general, practical palladium-catalyzed cyanation of (hetero)aryl chlorides and bromides
Senecal, Todd D.,Shu, Wei,Buchwald, Stephen L.
supporting information, p. 10035 - 10039 (2013/10/01)
Playing it safe: The nontoxic cyanide source K4[Fe(CN) 6]×3 H2O can be used for the cyanation of (hetero)aryl halides. The application of palladacycle catalysts prevents poisoning during catalyst formation, thereby allowing for low catalyst loadings, fast reaction times, and wide heterocyclic substrate scope.
