944904-43-2 Usage
Uses
Used in Pharmaceutical Industry:
3-Amino-6-trifluoromethyl-pyridin-2-ol is utilized as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique structure and the trifluoromethyl group's influence on its properties make it a valuable component in the development of new medications.
Used in Medicinal Chemistry Research:
3-Amino-6-trifluoromethyl-pyridin-2-ol is also studied for its potential biological activities, such as its role as an antifungal and antibacterial agent. The exploration of these properties is crucial for identifying new therapeutic agents and understanding their mechanisms of action, which can lead to advancements in treating various infections and diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 944904-43-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 944904-43:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*4)+(2*4)+(1*3)=192
192 % 10 = 2
So 944904-43-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H5F3N2O/c7-6(8,9)4-2-1-3(10)5(12)11-4/h1-2H,10H2,(H,11,12)
944904-43-2Relevant articles and documents
HMOX1 inducers
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Page/Page column 21; 150, (2020/09/18)
The present invention is related to compounds of structure (I) as heme oxygenase 1 (HMOX 1) inducers. The present invention is also related a method of controlling the activity or the amount, or both the activity and the amount, of heme-oxygenase 1 in a mammalian subject. The definitions of the variables are provided herein.
Catalytic hydrogenation of 3-amino-6-(trifluoromethyl)-5,6-dihydropyridin- 2(1 H)-ones and its use in the synthesis of trifluoromethyl-containing mimetics of ornithine and thalidomide
Tolmachova, Nataliya A.,Dolovanyuk, Violetta G.,Gerus, Igor I.,Kondratov, Ivan S.,Polovinko, Vitaliy V.,Bergander, Klaus,Haufe, Guenter
experimental part, p. 1149 - 1156 (2011/06/20)
A series of 3-amino-6-(trifluoromethyl)-5,6-dihydropyridin-2(1H)-ones and 6-hydroxy-5,6-dihydropyridin-2(1H)-ones were hydrogenated to give the corresponding piperidinones. These lactams were used for the synthesis of novel trifluoromethyl-containing ornithine analogues and thalidomide mimetics. Georg Thieme Verlag Stuttgart.
