944906-24-5 Usage
Description
1-(Pyrimidin-2-yl)ethanamine is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds. It features a pyrimidine ring attached to an ethanamine group, which contributes to its reactivity and potential applications in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
1-(Pyrimidin-2-yl)ethanamine is used as a synthetic reagent for the production of benzimidazole derivatives, which are known as phosphodiesterase 10A (PDE10A) inhibitors. These inhibitors have demonstrated efficacy in the treatment of cognitive and negative symptoms associated with schizophrenia, offering a valuable therapeutic option for patients suffering from this mental disorder.
Check Digit Verification of cas no
The CAS Registry Mumber 944906-24-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 944906-24:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*6)+(2*2)+(1*4)=195
195 % 10 = 5
So 944906-24-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H9N3/c1-5(7)6-8-3-2-4-9-6/h2-5H,7H2,1H3
944906-24-5Relevant articles and documents
OXAZOLONE AND PYRROLIDINONE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS
-
Page/Page column 24, (2010/12/31)
Compounds of the formula 1: or a pharmaceutically acceptable salt thereof, wherein, X, Y, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
