94498-99-4Relevant academic research and scientific papers
Construction of β to carbonyl stereogenic centres by asymmetric 1,4-addition of alkylzirconocenes to dienones and ynenones
Gao, Zhenbo,Fletcher, Stephen P.
, p. 3601 - 3604 (2018)
Copper-catalyzed asymmetric 1,4-addition of alkylzirconium species to linear α,β,γ,δ unsaturated dienones and ynenones is reported. A variety of alkyl nucleophiles are introduced with good yields and excellent regio- and enantio-selectivities to give tertiary carbon centres bearing multiple functional groups. The method is also applicable to an ynethioate with ee's over 96%.
Thiol esters in organic synthesis. XVI. Formation of α,β-unsaturated thiol esters via a Wadsworth-Emmons process
Liu, Hsing-Jang,Rose, Patricia A.,Sasaki, Doug J.
, p. 934 - 936 (2007/10/02)
α,β-Unsaturated thiol esters could be readily prepared via a Wadsworth-Emmons reaction using diethyl alkylthiocarbonylmethylphosphonate, which proved to be superior in reactivity to the corresponding Wittig reagent. Key words: α,β-unsaturated thiol esters
