945-43-7

Basic information

• Product Name: 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE
• Synonyms: 6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERINE MONOHYDROCHLORIDE;6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIN HYDROCHLORIDE;2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE;2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE HYDROCHLORIDE;2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE HYDROCHLORIDE;2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE;2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride;6,7-DIMETHYL-5,6,7,8-TETRAHYDRO-PTERINE MONOHYDROC
• CAS NO: 945-43-7
• Molecular Formula: C₈H₁₃N₅O*2ClH
• Molecular Weight: 231.68
• EINECS: 213-413-8
• Product Categories: Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Quinazolines
• Mol File: 945-43-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 244-247 °C (dec.)(lit.)
• Boiling Point: 349°Cat760mmHg
• Flash Point: 164.9°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 4.85E-05mmHg at 25°C
• Refractive Index: 1.79
• Storage Temp.: −20°C
• CAS DataBase Reference: 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE(945-43-7)
• EPA Substance Registry System: 2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE MONOHYDROCHLORIDE(945-43-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41-37/38
• Safety Statements: 26-36-36/37/39-39
• Hazardous Substances Data: 945-43-7(Hazardous Substances Data)

Usage

Biochem/physiol Actions

Synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4).

InChI:InChI=1/C8H13N5O/c1-3-4(2)11-6-5(10-3)7(14)13-8(9)12-6/h3-4,10H,1-2H3,(H4,9,11,12,13,14)

Upstream product

• 102093-98-1 6,7-dimethyldihydropterin hydrogen sulfate 
• 611-55-2 6,7-Dimethylpterin 
• 101092-03-9 2-amino-4-benzyloxy-6,7-dimethylpteridine 
• 36972-94-8 6,7-dimethyl-4-trimethylsiloxy-2-trimethylsilylaminopteridine 

Downstream Products

• 172758-00-8 6,7-dimethyl-5-nicotinoyl-5,6,7,8-tetrahydropterin 

Relevant articles and documents

Spectroscopic Evidence for the Redox Reaction between Copper(II) and a Pterin Cofactor Model, 6,7-Dimethyl-5,6,7,8-tetrahydropterin

The reactions of Cu(II) with 6,7-dimethyl-5,6,7,8-tetrahydropterin dihydrochloride (H4DMP*2HCl) in CH3OH-CH3CN have been investigated by spectroscopic methods.The redox reaction in the 1:1 Cu(II)-H4DMP*2HCl system has been established by detection of the protonated trihydropterin radical (H4DMP radical cation) and its disproportionation products.

SYNTHESIS OF QUINONOID 6-METHYL AND 6,7-DIMETHYLDIHYDROPTERINS

Quinonoid 6-methyl and 6,7-dimethylpterins were synthesized by the chemical oxidation.Some of their properties are described.