945006-71-3

Upstream product

• 883458-73-9 1-benzyloxymethyl-2-methylsulfanyl-4-(N-methoxyimino-1-chloromethyl)-5-vinylimidazole 
• 883458-72-8 1-benzyloxymethyl-2-methylsulfanyl-5-vinylimidazole-4-carboxylic acid 
• 883458-74-0 1-benzyloxymethyl-4-chloro-2-methylsulfanyl-1H-imidazo[4,5-c]pyridine 

Downstream Products

• 883458-79-5 2-azido-1-benzyloxymethyl-4-chloro-1H-imidazo[4,5-c]pyridine 
• 883458-80-8 2-amino-1-benzyloxymethyl-4-chloro-1H-imidazo[4,5-c]pyridine 

Relevant academic research and scientific papers

Application of a 6π-1-azatriene electrocyclization strategy to the total synthesis of the marine sponge metabolite ageladine A and biological evaluation of synthetic analogues

(Chemical Equation Presented) A 12-step synthesis of the angiogenesis inhibitory marine metabolite ageladine A is reported. The key steps include a 6π-1-azatriene electrocyclization for formation of the pyridine ring and a Suzuki-Miyaura coupling of N-Boc

Total synthesis of ageladine A, an angiogenesis inhibitor from the marine sponge Agelas nakamurai

A 12-step total synthesis of the tricyclic heteroaromatic marine metabolite ageladine A has been achieved using a 6π-azaelectrocyclization and a Suzuki-Miyaura coupling of N-Boc-pyrrole-2-boronic acid with a chloropyridine as key steps.