94501-18-5Relevant academic research and scientific papers
Copper(I)-Catalyzed Chemoselective Reduction of Benzofuran-2-yl Ketones to Alcohols with B2pin2 via a Domino-Borylation-Protodeboronation Strategy
Xuan, Qingqing,Kong, Weiguang,Song, Qiuling
, p. 7602 - 7607 (2017/07/26)
A novel copper(I)-catalyzed chemoselective reduction of the carbonyls of benzofuran-2-yl ketones over furan rings with B2pin2 has been developed. This reaction proceeded under mild conditions. High valuable secondary alcohol derivatives of benzofurans were obtained in good to excellent yields with a broad substrate scope. The mechanistic studies suggested that a domino-borylation-protodeboronation pathway was involved in this reaction.
A straightforward conversion of aurones to 2-benzoylbenzofurans: Transformation of one class of natural products into another
Yahiaoui, Samir,Peuchmaur, Marine,Boumendjel, Ahcne
, p. 7703 - 7707 (2011/10/12)
The naturally occurring aurones (2-benzylidene-3(2H)-benzofuran-3-ones) can be easily converted to another class of natural products 2-benzoylbenzo[b] furans, via an effective reduction, acid-mediated rearrangement, and oxidation cascade. This easy conver
Enantioselective reduction of benzofuranyl aryl ketones
Carpenter, Ian,Clarke, Matthew L.
supporting information; experimental part, p. 65 - 68 (2011/02/25)
Enantioselective transfer hydrogenation of benzofuranyl aryl ketones proceeds with moderate to good enantioselectivity even when the aryl group is not sterically differentiated by ortho-substituents. The best results are obtained with substrates that are functionalised by electron-withdrawing aryl groups that contrast with the electron-rich benzofuran, which is consistent with [Ru-ArC-H]·Ar π interactions acting as a control element. Enantioselective pressure hydrogenation gives lower enantioselectivity irrespective of electronic effects, unless the aryl group is ortho-substituted, in which case up to 86% ee can be realised. Georg Thieme Verlag Stuttgart - New York.
A concerted synthesis of hydroxychalcones, flavanones and benzo[b]furans through palladium-catalysed reactions
De, Mahuya,Majumdar, Dyuti P.,Kundu, Nitya G.
, p. 665 - 674 (2007/10/03)
A convenient palladium-catalysed procedure for the synthesis of o-hydroxychalcones, flavanones and benzo[b]furans is described where o-iodophenyl acetate was used as a common precursor.
Palladium-catalysed heteroannulation with acetylenic compounds: Synthesis of benzofurans
Kundu, Nitya G.,Pal, Manojit,Mahanty, Jyan S.,De, Mahuya
, p. 2815 - 2820 (2007/10/03)
A detailed study of the heteroannulation of 0-iodophenol with acetylenic substrates through palladiumcopper catalysis leading to the synthesis of the 2-substituted benzofurans 21-29 is reported. An acylic compound 30 has been isolated and proved to be an intermediate in the synthesis of the benzofurans. Some of the benzofurans have been transformed into biologically active compounds.
Palladium-catalysed Heteroannulation of Acetylenic Compounds: a Facile Method for the Synthesis of Benzofurans
Kundu, Nitya G.,Pal, Manojit,Mahanty, Jyan S.,Dasgupta, Swapan K.
, p. 41 - 42 (2007/10/02)
A convenient and general method for the synthesis of benzofurans from o-iodophenol and acetylenic compounds under palladium-catalysed conditions is described.
