945033-99-8

Upstream product

• 139301-93-2 9-((3aR,4R,6R,6aR)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine 
• 945033-96-5 5'-O-t-butyldimethylsilyl-8-iodo-2',3'-O-isopropylideneadenosine 
• 945033-98-7 8-allyl-6-N-bis(t-butoxycarbonyl)-5'-O-t-butyldimethylsilyl-2',3'-O-isopropylideneadenosine 
• 124097-05-8 benzyl (2S)-2-[(tert-butoxycarbonyl)amino]-4-pentenoate 

Downstream Products

• 945034-01-5 6-N-bis(t-butoxycarbonyl)-8-(O-benzyl-N-[t-butoxycarbonyl]-L-2''-E/Z-crotylglycin-6''-yl)-2',3'-O-isopropylideneadenosine 
• 945034-03-7 6-N-bis(t-butoxycarbonyl)-8-(O-benzyl-N-[t-butoxycarbonyl]-L-2''-E/Z-crotylglycin-6''-yl)-2',3'-O-isopropylidene-5'-O-sulfamoyladenosine 

Relevant academic research and scientific papers

Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules

Macrocyclic aminoacyl-AMP analogs have been developed to inhibit non-ribosomal peptide synthetase amino acid adenylation domains selectively by mimicking a cisoid ligand binding conformation observed in crystal structures. In contrast, these macrocycles d