945034-41-3Relevant academic research and scientific papers
Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1)
Castellano, Sabrina,Milite, Ciro,Ragno, Rino,Simeoni, Silvia,Mai, Antonello,Limongelli, Vittorio,Novellino, Ettore,Bauer, Ingo,Brosch, Gerald,Spannhoff, Astrid,Cheng, Donghang,Bedford, Mark T.,Sbardella, Gianluca
scheme or table, p. 398 - 414 (2010/11/17)
Here we report the synthesis of a number of compounds structurally related to arginine methyltransferase inhibitor 1 (AMI-1). The structural alterations that we made included: 1) the substitution of the sulfonic groups with the bioisosteric carboxylic gro
Highly efficient synthesis and chemical separation of 5-amino- and 7-amino-4-hydroxy-2-naphthoic acids
Castellano, Sabrina,Milite, Ciro,Campiglia, Pietro,Sbardella, Gianluca
, p. 4653 - 4655 (2008/03/12)
5-Amino- and 7-amino-4-hydroxy-2-naphthoic acids were synthesized for the first time via a microwave-assisted pathway. The separation of the two isomers was then conveniently achieved by exploiting their different reactivities with CDI.
SELECTIVE INHIBITORS FOR TRANSFERASES
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Page/Page column 19; 21, (2008/06/13)
A pharmaceutical composition comprising a compound of formula I or II and a pharmaceutically acceptable carrier. Methods for treating a proliferative disorder mediated by a methyl transferase comprising administering an anti-proliferative effective amount
