94511-13-4

Basic information

• Product Name: Benzenesulfonamide, N-(2-benzoyl-3-benzofuranyl)-4-methyl-
• CAS NO: 94511-13-4
• Molecular Formula: C22H17NO4S
• Molecular Weight: 391.447
• Mol File: 94511-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-(2-benzoyl-3-benzofuranyl)-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-(2-benzoyl-3-benzofuranyl)-4-methyl-(94511-13-4)
• EPA Substance Registry System: Benzenesulfonamide, N-(2-benzoyl-3-benzofuranyl)-4-methyl-(94511-13-4)

Safety Data

• Hazardous Substances Data: 94511-13-4(Hazardous Substances Data)

Upstream product

• 49615-93-2 (3-aminobenzo[b]furan-2-yl)phenylmethanone 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 34823-86-4 GTP-14564 
• 94510-85-7 C₄₄H₃₄N₄O₆S₂ 
• 94511-16-7 N-Acetyl-N-{2-[(acetyl-hydrazono)-phenyl-methyl]-benzofuran-3-yl}-4-methyl-benzenesulfonamide 
• 98-10-2 benzenesulfonamide 
• 94510-80-2 methylhydrazone of 2-benzoyl-3-p-toluenesulfonylamidobenzofuran 
• 94510-81-3 methylhydrazone of 2-benzoyl-3-p-toluenesulfonylamidobenzofuran 
• 94510-82-4 (Z)-dimethylhydrazone of 2-benzoyl-3-p-toluensulfonylamidobenzofuran 
• 94510-83-5 (E)-dimethylhydrazone of 2-benzoyl-3-p-toluensulfonylamidobenzofuran 
• 94511-17-8 3-phenyl-8b-p-toluenesulfonylamido-3a,8b-dihydro-1H-benzofuro<3,2-c>pyrazole 
• 94511-15-6 (Z)-hydrazone of 2-benzoyl-3-p-toluenesulfonylamidobenzofuran 
• 19726-12-6 3⁽⁵⁾-(2-hydroxyphenyl)-5⁽³⁾-phenylpyrazole 

Relevant articles and documents

Reaction of 2-acyl-3-aminobenzofurans with hydrazines

While 2-acetyl and 2-benzoyl-3-aminobenzofurans did not react with hydrazine, monomethyl- and N,N-dimethylhydrazine to give the related hydrazones, their 3-N-(p-toluenesulfonyl) derivatives afforded them smoothly in good yields. Depending upon reaction conditions, products arising from hydrazone cyclization to benzofuropyrazoles and/or from furan ring cleavage at the C2-O bond to give 5-(2-hydroxyphenyl)pyrazoles were also formed. The formation of these products depends upon hydrazones configuration and is discussed. Only (E)-isomers appear to undergo furan ring opening. In acidic media at room temperature either the hydrazones or the monomethylhydrazones gave the same related α-azines. Microanalyses, ir, uv, 1H-nmr and ms spectra are in agreement with the proposed structures.