94518-63-5Relevant academic research and scientific papers
Three-Component Cyclocondensations. Two Methods for the Efficient Preparation of 5-Aminothiazolium Salts via the Reaction of Isocyanides Either with Dimethylthioformamide and Imino Chloro Sulfides or Benyaldimines and Aryl Chlorothioformates
Berree, Fabienne,Malvaut, Yvelise,Marchand, Evelyne,Morel, Georges
, p. 6022 - 6029 (2007/10/02)
Treatment of imino chloro sulfides with dimethylthioformamide and isocyanides at room temperature provides selectively the 5-amino-4-(dimethylamino)-2-(methylthio) (or phenylthio)thiazolium salts.Similarly, the reactions of p-tolyl chlorothionoformate and phenyl chlorodithioformate with a mixture of benzaldimine and isocyanide afford rapidly the 5-amino-4-phenylthiazolium salts.We suggest that these reactions involve the N-(thiocarbonyl)formamidinium and benzylideniminium chlorides as transient intermediates, which are trapped by isocyanides according to a cycloaddition process.The structure of the thiazolium salts and some of their reactivities are discussed.
C-(Methoxycarbonyl)ketene N-Imidoylimines. Synthesis and Rearrangement into Methyl 4,6-Diazahepta-2,4,6-trienoates. Cycloaddition Reactions with Isocyanides: Preparation of Imidazolines
Morel, Georges,Marchand, Evelyne,Foucaud, Andre
, p. 771 - 778 (2007/10/02)
The ketene N-imidoylimines 12 are shown to be transitory intermediates formed by the reaction of isocyanides with sulfides 1 or by the reaction of imino chloro sulfides with sodium salts of α-cyano esters 3.When the nitrogen atom of the imidoyl group bear
