94521-90-1

Basic information

• Product Name: ethyl 2-methyl-2-phenylacetoimidate hydrochloride
• Synonyms: ethyl 2-methyl-2-phenylacetoimidate hydrochloride
• CAS NO: 94521-90-1
• Molecular Weight: 213.707
• Mol File: 94521-90-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 2-methyl-2-phenylacetoimidate hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-methyl-2-phenylacetoimidate hydrochloride(94521-90-1)
• EPA Substance Registry System: ethyl 2-methyl-2-phenylacetoimidate hydrochloride(94521-90-1)

Safety Data

• Hazardous Substances Data: 94521-90-1(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1823-91-2 1-phenylethyl cyanide 

Downstream Products

• 216172-65-5 [2(1'RS),4S,5S]-4,5-dihydro-4,5-diphenyl-2-(1'-phenylethyl)-1H-imidazole 
• 145144-64-5 [5(4'R*,5'R*)]-5-(4',5'-dihydro-4',5'-diphenyl-1H-imidazol-2'-yl)-5-phenylhexan-1-ol 
• 145144-57-6 [2(1'RS),4R*,5R*]-4,5-dihydro-4,5-diphenyl-2-(1'-phenylethyl)-1H-imidazole 
• 110010-47-4 [2-(1-Phenyl-ethyl)-1H-imidazol-4-yl]-methanol 
• 701902-76-3 4-Chloromethyl-2-(1-phenyl-ethyl)-1H-imidazole 
• 110010-82-7 [2-(1-Phenyl-ethyl)-1H-imidazol-4-yl]-acetonitrile 

Relevant articles and documents

Stereoselective synthesis of quaternary benzylic carbons using C2 symmetric imidazolines and tetrahydrofuran as electrophile

Alkylative ring opening of tetrahydrofuran in the presence of 9-BBN triflate is studied. Dianions derived from C2 symmetric imidazolines induce excellent to modest acyclic diastereoselectivity to form quaternary benzylic centers, using the 9-BBN triflate/THF system or methyl iodide as electrophiles. The direction of the stereoinduction is consistent in both cases. Absolute configuration for the newly created stereogenic center was established by chemical correlation. Low-temperature NMR studies of the dilithiated intermediates 42 and 43 suggest the presence of N- and C- metalated compounds, where the metal-bearing benzylic carbon is sp3 hybridized.

Research on hypocholesterolemic substances: synthesis of amidines

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