945333-37-9Relevant academic research and scientific papers
TiO2-SiO2 nanocomposite-promoted efficient cyclocondensation reaction of arylmethylidenepyruvic acids with dimedone in aqueous media
Sadegh-Samiei, Sepehr,Abdolmohammadi, Shahrzad
, p. 1155 - 1159 (2018)
This work focuses on the successful synthesis of 4-aryl-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydro-2-quinolinecarboxylic acids through a condensation reaction of arylmethylidenepyruvic acids with ammonium acetate and dimedone using a catalytic amount of TiO2–SiO2 nanocomposite (15 mol%) at room temperature in aqueous media. The principal advantage of this procedure is the relatively high yields (94–98%) with short reaction times (2 hr), under mild reaction conditions and with low environmental impact.
TiO2 nanoparticles as an effective catalyst for the synthesis of hexahydro-2-quinolinecarboxylic acids derivatives
Abdolmohammadi, Shahrzad
experimental part, p. 1003 - 1006 (2012/09/22)
The one-pot three-component reaction of arylmethylidenepyruvic acids, 1,3-cyclohexandiones and ammonium acetate provides an economical and efficient synthetic route to 5-oxo-4-aryl-1,4,5,6,7,8-hexahydro-2-quinolinecarboxylic acid 4 under solvent-free cond
