945388-85-2Relevant academic research and scientific papers
Novel and efficient synthesis of 4-substituted-1,2,4-triazolidine-3,5- diones from anilines
Mallakpour, Shadpour,Rafiee, Zahra
, p. 1927 - 1934 (2008/02/04)
A simple and efficient three-step synthetic procedure for the preparation of 4-substituted phenyl derivatives of 1,2,4-triazolidindiones (urazoles), starting from anilines, has been developed. In this method, aniline derivatives were reacted with 4-nitrophenyl chloroformate to provide corresponding carbamate derivatives. In the second step, semicarbazide derivatives were prepared from these carbamates by reaction with ethyl carbazate. The cyclization reaction of corresponding semicarbazides furnished 1,2,4-triazolidindiones in high yields. Copyright Taylor & Francis Group, LLC.
