945494-69-9Relevant academic research and scientific papers
Asymmetric hydroformylation of vinyl acetate: Application in the synthesis of optically active isoxazolines and imidazoles
Thomas,Axtell, Alex T.,Klosin, Jerzy,Wei, Peng,Rand, Cynthia L.,Clark, Thomas P.,Landis, Clark R.,Abboud, Khalil A.
, p. 2665 - 2668 (2008/02/09)
Equation Presented (R)- and (S)-2-(Acetyloxy)-propanal were prepared [93.8% ee, 102 b/l for (R), 96.9% ee, 149 b/l for (S)] via asymmetric hydroformylation of vinyl acetate on a 150-180 g scale and were used as the starting materials in the synthesis of chiral isoxazoline and imidazole derivatives which proceeded without racemization of the chiral center.
