945528-22-3Relevant academic research and scientific papers
Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy
De Moor, Olivier,Dorgan, Colin R.,Johnson, Peter D.,Lambert, Adam G.,Lecci, Cristina,Maillol, Carole,Nugent, Gary,Poignant, Severine D.,Price, Paul D.,Pye, Richard J.,Storer, Richard,Tinsley, Jonathon M.,Vickers, Richard,Well, Renate Van,Wilkes, Fraser J.,Wilson, Francis X.,Wren, Stephen P.,Wynne, Graham M.
, p. 4828 - 4831 (2011/09/16)
Families of 2-arylbenzotriazoles and 2-arylindazoles that show positive effects in screens predictive of endogenous utrophin upregulation have been identified. Synthesis and structure-activity relationships are described leading to compounds with attractive in vitro profiles.
TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY
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Page/Page column 39, (2010/11/28)
There are disclosed compound of Formula (I) or (II) wherein A1, A2, A3, A4and A5, which may be the same or different, represent N or CR1, R9 represents - L -R3, in whi
