945530-74-5Relevant articles and documents
Expanding Benzoxazole-Based Inosine 5′-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents
Chacko, Shibin,Boshoff, Helena I. M.,Singh, Vinayak,Ferraris, Davide M.,Gollapalli, Deviprasad R.,Zhang, Minjia,Lawson, Ann P.,Pepi, Michael J.,Joachimiak, Andrzej,Rizzi, Menico,Mizrahi, Valerie,Cuny, Gregory D.,Hedstrom, Lizbeth
, p. 4739 - 4756 (2018/05/23)
New drugs and molecular targets are urgently needed to address the emergence and spread of drug-resistant tuberculosis. Mycobacterium tuberculosis (Mtb) inosine 5′-monophosphate dehydrogenase 2 (MtbIMPDH2) is a promising yet controversial potential target