945537-04-2

Upstream product

• 111-71-7 heptanal 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 

Downstream Products

• 1009311-46-9 C₂₀H₂₇NO₄ 
• 1009311-49-2 C₂₂H₃₁NO₄ 
• 1009311-47-0 C₂₂H₃₁NO₄ 
• 475627-57-7 (R)-3-((S)-1-Methoxy-2-oxo-heptyl)-4-phenyl-oxazolidin-2-one 
• 475627-55-5 (R)-3-((R)-1-Methoxy-2-oxo-heptyl)-4-phenyl-oxazolidin-2-one 
• 475627-49-7 3-Chloro-benzoic acid 2-hydroxy-1-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-heptyl ester 

Relevant academic research and scientific papers

A highly regio- and stereoselective synthesis of ?±-fluorinated imides via fluorination of chiral enamides

A highly ??-facial selective and regioselective fluorination of chiral enamides is described. The reaction involves an enantioselective fluorination exclusively at the electron-rich enamide olefin with N-F reagents such as Selectfluor and N-fluoro-benzenesulfonimide [NFSI] accompanied by trapping of the ?2-fluoro-iminium cationic intermediate with water. The resulting N,O-hemiacetal could be oxidized using Dess-Martin periodinane, leading to an asymmetric sequence for syntheses of chiral ?±-fluoro-imides and optically enriched ?±-fluoro-ketones.

A mutually π-facial selective cyclopropanation of chiral enamides using dirhodium(ll) carbenoids

A mutually π-facial selective cyclopropanation of chiral enamides using dirhodium(ll) carbenoids is described here. This work illustrates the influence of enamide substituents on stereoselectivity and reveals insights into this cyclopropanation.

Stereoselective Simmons-Smith cyclopropanation of chiral enamides

(Chemical Equation Presented) Efficient and practical access to chiral aminocyclopropanes is secured by the title reaction (see example). Both E and Z enamides undergo the cyclopropanation with high diastereoselectivity (d.r. up to > 95:5). The applicatio