94559-03-2

Basic information

• Product Name: (S)-2-(4-Chloro-2-methyl-phenoxy)-propionic acid (R)-1-pyridin-4-yl-ethyl ester
• Synonyms: (S)-2-(4-Chloro-2-methyl-phenoxy)-propionic acid (R)-1-pyridin-4-yl-ethyl ester
• CAS NO: 94559-03-2
• Molecular Weight: 319.788
• Mol File: 94559-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(4-Chloro-2-methyl-phenoxy)-propionic acid (R)-1-pyridin-4-yl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(4-Chloro-2-methyl-phenoxy)-propionic acid (R)-1-pyridin-4-yl-ethyl ester(94559-03-2)
• EPA Substance Registry System: (S)-2-(4-Chloro-2-methyl-phenoxy)-propionic acid (R)-1-pyridin-4-yl-ethyl ester(94559-03-2)

Safety Data

• Hazardous Substances Data: 94559-03-2(Hazardous Substances Data)

Upstream product

• 27854-88-2 (R)-1-(4-pyridinyl)ethanol 
• 42383-63-1 2-(4-Chlor-2-methylphenoxy)propionsaeureanhydrid 

Downstream Products

• 16484-77-8 (R)-Mecoprop 
• 25333-13-5 (S)-mecoprop 

Relevant articles and documents

Preparation of Optical Active 2-(Aryloxy)propionic Acids by Kinetic Resolution. - Herbizides

2-(Aryloxy)propionic anhydrides 2 were transformed with 70-90percent stereoselectivity into the R,S- or S,R-diastereomeric esters 4, respectively, on reaction with stoichiometric amounts of optical active 1-(4-pyridyl)ethanol (3).The acid 1 set free in one mol equivalent during this reaction was mainly the other enantiomer in 62-72percent optical yields.By treatment with boiling acetic anhydride and pyridine the acid 1 is transformed back into racemic anhydride 2.The ester 4 was hydrolyzed with aqueous acid to optical active 1 with regeneration of the optical active alcohol 3.In this way a quantitative transformation of racemic acids 1 into that enantiomer which is an active herbizide is possible using 3 as optical active auxiliary material.