945608-15-1

Basic information

• Product Name: 1H-PYRROLO[2,3-B]PYRIDINE,3-IODO-1-METHYL-2-PHENYL-
• Synonyms: 1H-PYRROLO[2,3-B]PYRIDINE,3-IODO-1-METHYL-2-PHENYL-;3-iodo-1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridine
• CAS NO: 945608-15-1
• Molecular Formula: C₁₄H₁₁IN₂
• Molecular Weight: 334.15
• Mol File: 945608-15-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-PYRROLO[2,3-B]PYRIDINE,3-IODO-1-METHYL-2-PHENYL-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-PYRROLO[2,3-B]PYRIDINE,3-IODO-1-METHYL-2-PHENYL-(945608-15-1)
• EPA Substance Registry System: 1H-PYRROLO[2,3-B]PYRIDINE,3-IODO-1-METHYL-2-PHENYL-(945608-15-1)

Safety Data

• Hazardous Substances Data: 945608-15-1(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-b]pyridine,3-iodo-1-methyl-2-phenyl- is a chemical compound with the molecular formula C13H11IN. It is a pyrrolopyridine derivative that contains an iodine atom, a methyl group, and a phenyl group. 1H-Pyrrolo[2,3-b]pyridine,3-iodo-1-methyl-2-phenyl- is commonly used in organic synthesis and pharmaceutical research. Its unique structure and functional groups make it a valuable building block for the synthesis of various biologically active molecules and pharmaceutical compounds. It has potential applications in the development of new drugs, including antiviral, anticancer, and antibacterial agents. Additionally, it has been studied for its potential role in the treatment of neurodegenerative diseases and other medical conditions.

Upstream product

• 521984-94-1 1-methyl-2-phenyl-1H-pyrrolo-[2,3-b]pyridine 
• 214342-66-2 3-iodo-N,N-dimethyl-pyridin-2-amine 
• 113975-22-7 2-fluoro-3-iodopyridine 
• 13534-99-1 2-Amino-3-bromopyridine 
• 536-74-3 phenylacetylene 
• 74-88-4 methyl iodide 
• 10586-52-4 2-phenyl-1H-pyrrolo[2,3-b]pyridine 
• 98-88-4 benzoyl chloride 
• 1603-40-3 3-methylpyridin-2-ylamine 
• 23612-46-6 N-(3-methylpyridin-2-yl)benzamide 
• 116026-94-9 2--3-pyridinecarboxaldehyde 
• 945607-77-2 [3-(2,2-dichlorovinyl)-pyridin-2-yl]-methyl-amine 
• 945607-94-3 C₁₃H₁₆Cl₂N₂O₂ 
• 945607-75-0 [3-(2,2-dibromovinyl)-pyridin-2-yl]-methyl-amine 

Downstream Products

• 1009104-85-1 ((E)-1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one) 
• 1439397-11-1 1-(4-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)cyclobutanamine 
• 1439397-16-6 tert-butyl 1-(4-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)cyclobutylcarbamate 
• 1009104-85-1 SIS₃ 

Relevant articles and documents

Synthesis of 3-Halo-7-azaindoles through a 5- endo -dig Electrophilic Cyclization Reaction

Biologically useful 7-azaindoles were synthesized by electrophilic cyclization of 3-alkynyl- N, N -dimethylpyridine-2-amines with molecular iodine. By this simple atom-economical approach under ambient reaction conditions, a library of interesting 3-iodo-7-azaindoles were synthesized in high yields. To synthesize the corresponding 3-bromo- and 3-chloro-7-azaindoles, an environmentally benign copper-mediated cyclization was employed, with inexpensive, nontoxic, and noncorrosive sodium chloride and sodium bromide as the sources of chlorine and bromine, respectively.

BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula 1: wherein Het, X, R1 and R2 are as defined herein.

A general modular method of azaindole and thienopyrrole synthesis via Pd-catalyzed tandem couplings of gem-dichloroolefins

(Chemical Equation Presented) A palladium-catalyzed reaction of gem-dichloroolefins and a boronic acid via a tandem intramolecular C-N and intermolecular Suzuki coupling process gave corresponding substituted azaindoles or thienopyrroles. This method is a