94565-10-3Relevant academic research and scientific papers
Facile and direct halogenation of 1,2,3-triazoles promoted by a KX-oxone system under transition metal free conditions
Rai, Vishakha,Sorabad, Ganesh Shivayogappa,Maddani, Mahagundappa Rachappa
, p. 3969 - 3973 (2021)
A convenient and efficient oxidative halogenation of 4-aryl 1,2,3-triazoles is realized at ambient temperature under transition metal free conditions. In this methodology, halogenation is achieved by using readily available potassium halides (KBr, KCl, and KI) with oxone as an oxidant under mild reaction conditions and halogenated products are obtained in good to excellent yields. In addition, the synthesized halogenated triazoles are applied for the synthesis of functionalized molecules.
HETEROCYCLIC COMPOUNDS CONTAINING DIAZO AND CYANO GROUPS. 1. DIAZOACETONITRILE DERIVATIVES IN THE SYNTHESIS OF 5-HALO-1H-1,2,3-TRIAZOLES
Shafran, Yu. M.,Bakulev, V. A.,Mokrushin, V. S.,Alekseev, S. G.
, p. 1038 - 1043 (2007/10/02)
Carbonyl-substituted derivatives of diazoacetonitrile have been obtained by the diazotation of amines and by diazo-group transfer which, under the action of hydrogen halide, have been converted into 4-carbonyl-substitued 5-halo-1H-1,2,3-triazoles.The stru
