945736-78-7

Basic information

• Product Name: 1-[(R)-((E)-1-but-2-enyl)tetradecyloxymethyl]-4-methoxybenzene
• Synonyms: 1-[(R)-((E)-1-but-2-enyl)tetradecyloxymethyl]-4-methoxybenzene
• CAS NO: 945736-78-7
• Molecular Weight: 388.634
• Mol File: 945736-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(R)-((E)-1-but-2-enyl)tetradecyloxymethyl]-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(R)-((E)-1-but-2-enyl)tetradecyloxymethyl]-4-methoxybenzene(945736-78-7)
• EPA Substance Registry System: 1-[(R)-((E)-1-but-2-enyl)tetradecyloxymethyl]-4-methoxybenzene(945736-78-7)

Safety Data

• Hazardous Substances Data: 945736-78-7(Hazardous Substances Data)

Upstream product

• 124-25-4 myristylaldehyde 
• 862472-84-2 (2E,5R)-octadec-2-en-5-ol 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 

Downstream Products

• 945736-75-4 (R)-3-(4-methoxybenzyloxy)hexadecanal 
• 945736-82-3 (2S,4S,6R)-2-[2-(4-hydroxyphenyl)ethyl]-2-methoxy-6-tridecyltetrahydropyran-4-ol 

Relevant articles and documents

Diastereodivergent strategies for the synthesis of homochiral aculeatins

(Chemical Equation Presented) We report concise and stereocontrolled syntheses of aculeatins (-)-A, (+)-B, (+)-D, and (+)-6-epi-D. Diastereodivergent 1,3-inductions in Mukaiyama aldol coupling contribute to reduce steps and to increase flexibility with reactants having sterically restricted proximal substituents (i.e., CH2), involving either a good anti or a moderate syn 1,3-induction, depending on the nature of protecting group (P). In addition, the 3,5-syn-diol-ketone resulting from concomitant deprotection of the β-alkoxy (Tr = trityl) group proves to be remarkably stable whereas the 3,5-anti diastereoisomer cyclizes spontaneously to the corresponding tetrahydropyran hemiketal, thus enabling a useful and facile separation. The second part of our study is devoted to improving the yield and the diastereoselectivity of the final phenolic oxidation reaction leading to aculeatins.