94577-08-9Relevant academic research and scientific papers
MgO nanoparticles as an efficient and reusable catalyst for aza-Michael reaction
Tajbakhsh, Mahmood,Farhang, Maryam,Hosseini, Ali Asghar
, p. 665 - 672 (2014)
MgO nanoparticles were prepared by an improved sol-gel technique which appeared to have narrow size distributions. The synthesized magnesium oxide nanoparticles were used as an efficient catalyst in aza-Michael reaction for addition of amines to a series of α,β-unsaturated carbonyl compounds and nitro olefins under solvent-free conditions at room temperature to afford high yields of the β-amino carbonyl and β-nitro amines. The catalyst can be recovered and reused at least five successive runs without loss of activity. Graphical abstract: [Figure not available: see fulltext.]
Stereoselective photocyclization to 2-aminocyclopropanols by photolysis of β-aminoketones and oxidative ring opening to enaminones
Weigel, Wilfried,Schiller, Sabine,Henning, Hans-Georg
, p. 7855 - 7866 (2007/10/03)
Irradiation of β-aminopropiophenones 1 leads to the formation of 2-aminocyclopropanols 2 which can undergo oxidative ring opening to give enaminones 3. The regioselectivity of cyclopropanol formation of the α-benzyl substituted 1 is determined by the preferred charge transfer interaction between the photoexcited benzoyl chromophore and the amino group. The photocyclizations of the α- or β-substituted 1 proceed stereoselectively. No photoracemization of the pure enantiomers of 1m, independent of the solvent polarity was observed. Aryl or alkyl substituents at the C(3)- or C(2)-ring atom stabilize the cyclopropanol derivatives. The formation of 3 indicates regioselective C(1)-C(2) ring opening of 2 probably by localization of the excitation energy.
