945828-45-5

Upstream product

• 945771-74-4 2-methyl-7-hydroxy-6-methoxy-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan 
• 558-13-4 carbon tetrabromide 
• 538-60-3 dibenzyl hydrogen phosphite 
• 905752-38-7 2-(t-butyldimethylsilyloxy)-7-isopropoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzofuran 
• 905752-37-6 2-(tert-butyldimethylsilyloxy)-7-acetoxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxybenzofuran 
• 905752-39-8 7-O-acyl-2-(t-butyldimethylsilyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan 
• 1007198-30-2 C₂₅H₃₂O₇Si 
• 905752-33-2 2-t-butyldimethylsilyl-7-isopropoxy-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan 
• 905752-32-1 2-t-butyldimethylsilyl-3-formyl-6-methoxy-7-isopropoxybenzofuran 
• 905752-30-9 7-O-acyl-2-bromo-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan 
• 25245-29-8 5-iodo-1,2,3-trimethoxybenzene 
• 17176-77-1 Dibenzyl phosphite 

Relevant academic research and scientific papers

METHOD FOR TREATING ACUTE MYELOID LEUKEMIA

The present invention relates to a method for the treatment of acute myeloid leukemia (AML) with medicaments useful for same. The medicaments can be pharmaceutical compositions or kits comprising compounds of the presently-described formula (I) or a salt,

Combination Therapy for Treating Proliferative Diseases

The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer.

COMBINATION TREATMENT PROTOCOL

The present disclosure provides a combination and a method for treating chronic lymphocytic leukemia (CLL).

A THERAPEUTIC PROTOCOL FOR TREATING OVARIAN CANCER

The present invention is directed to a pharmaceutical combination for treating proliferative disease comprising a compound of formula (I), or a salt, solvate or prodrug thereof, carboplatin or cisplatin, and gemcitabine. The present invention is further d

METHOD FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA

The present disclosure provides methods for treating chronic lymphocytic leukemia (CLL) with medicaments useful for same. The medicaments can be pharmaceutical compositions or kits comprising compounds of formula (I) or a salt, solvate or prodrug thereof.

COMBINATION THERAPY INVOLVING A VASCULAR DISRUPTING AGENT AND AN AGENT WHICH TARGETS HYPOXIA

The present invention provides a method for treating a proliferative disease in a patient. The method comprises administering to a patient in need thereof: a) a vascular disrupting agent and (b) at least one hypoxia targeting agent. Preferred combinations

Combination Therapy for Treating Proliferative Diseases

The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer.

TREATMENT OF MACULAR DEGENERATION

The present invention relates generally to methods for treating macular degeneration, and in particular age-related macular degeneration, involving the use of specific benzofuran based compounds.

SUBSTITUTED BENZOFURANS, BENZOTHIOPHENES, BENZOSELENOPHENES AND INDOLES AND THEIR USE AS TUBULIN POLYMERISATION INHIBITORS

The present invention relates generally to substituted benzofurans, benzothiophenes, and indoles and their use as tubulin polymerisation inhibitors.