945852-48-2Relevant academic research and scientific papers
Chiral phosphoric acid catalyzed asymmetric friedel-crafts alkylation of indoles with nitroolefins
Tang, Hong-Ying,Zhang, Zhong-Biao
experimental part, p. 2038 - 2046 (2011/11/30)
Asymmetric Michael-type Friedel-Crafts (F-C) alkylations of indoles with nitroolefins catalyzed by a chiral H8-BINOL-based phosphoric acid were investigated. The reactions took place very smoothly in the presence of only 5 mol-% of catalyst at
A convenient protocol for the synthesis of axially chiral Br?nsted acids
Bartoszek, Michael,Beller, Matthias,Deutsch, Jens,Klawonn, Markus,K?ckritz, Angela,Nemati, Navid,Pews-Davtyan, Anahit
, p. 1316 - 1322 (2008/09/17)
Partially hydrogenated binaphthol monophosphoric acids were prepared via an improved four-step sequence. It is demonstrated that typical protection and deprotection of the phenolic groups are dispensable. The vinyl-substituted derivative has been polymerized to give a novel polymerized organocatalyst.
Chiral Bronsted acid-catalyzed direct asymmetric Mannich reaction
Guo, Qi-Xiang,Liu, Hua,Guo, Chang,Luo, Shi-Wei,Gu, Yi,Gong, Liu-Zhu
, p. 3790 - 3791 (2008/02/03)
A chiral Bronsted acid-catalyzed direct asymmetric Mannich reaction has been described. Various phosphoric acids, prepared from BINOL and H8-BINOL derivatives, have been evaluated for catalyzing the direct Mannich reaction. In the presence of a
ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST
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Page/Page column 30, (2010/11/08)
A compound usable as an asymmetric synthesis catalyst which can be easily synthesized without using any metal such as a lanthanoid group element; a method of asymmetric synthesis with the compound; and a chiral compound obtained by the asymmetric synthesis method. A Broensted acid is used as a catalyst in asymmetric synthesis, the chiral Broensted acid being represented by formula (1) below or formula (3) below. The asymmetric synthesis method employs the catalyst. Asymmetric synthesis with the catalyst gives a chiral compound.
Highly enantioselective organocatalytic Biginelli reaction
Chen, Xiao-Hua,Xu, Xiao-Ying,Liu, Hua,Cun, Lin-Feng,Gong, Liu-Zhu
, p. 14802 - 14803 (2008/02/09)
A series of binol- and H8-binol-based phosphoric acids have for the first time been evaluated for their ability to catalyze Biginelli reactions of aldehydes, thiourea or urea, and β-keto esters. A new chiral phosphoric acid, derived from 3,3′-d
