945954-95-0

Basic information

• Product Name: 6-Bromo-3-methoxypyridine-2-carboxaldehyde
• Synonyms: 6-Bromo-3-methoxypyridine-2-carboxaldehyde;6-BroMo-3-Methoxy-2-pyridinecarboxaldehyde;6-BroMo-3-Methoxypicolinaldehyde;2-Pyridinecarboxaldehyde, 6-broMo-3-Methoxy-
• CAS NO: 945954-95-0
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03
• Mol File: 945954-95-0.mol

Chemical Properties

• Boiling Point: 301.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.606
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.47±0.10(Predicted)
• CAS DataBase Reference: 6-Bromo-3-methoxypyridine-2-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-3-methoxypyridine-2-carboxaldehyde(945954-95-0)
• EPA Substance Registry System: 6-Bromo-3-methoxypyridine-2-carboxaldehyde(945954-95-0)

Safety Data

• Hazardous Substances Data: 945954-95-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
6-Bromo-3-methoxypyridine-2-carboxaldehyde is used as a research compound for studying its properties and potential applications in chemical reactions and synthesis processes.
Used as an Intermediate in Pharmaceutical Synthesis:
6-Bromo-3-methoxypyridine-2-carboxaldehyde is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable building block for the development of new drugs.
Used as an Intermediate in Agrochemical Synthesis:
6-Bromo-3-methoxypyridine-2-carboxaldehyde is also used as an intermediate in the synthesis of agrochemicals, contributing to the development of new pesticides and other agricultural products.
Used in the Production of Heterocyclic Compounds:
6-Bromo-3-methoxypyridine-2-carboxaldehyde is used as a starting material in the production of heterocyclic compounds, which are important in various fields such as pharmaceuticals, agrochemicals, and materials science.
Used in the Development of New Materials:
Due to its unique structure and functional groups, 6-Bromo-3-methoxypyridine-2-carboxaldehyde has potential applications in the development of new materials with specific properties, such as conductivity, magnetism, or catalytic activity.
Used in the Development of Bioactive Molecules:
6-Bromo-3-methoxypyridine-2-carboxaldehyde can be utilized in the development of bioactive molecules with potential applications in medicine, agriculture, and other industries. Its unique structure allows for the design and synthesis of novel compounds with specific biological activities.

Upstream product

• 1256810-26-0 6-bromo-3-methoxypyridine-2-carboxylic acid 
• 945954-94-9 methyl 6-bromo-3-methoxypyridine-2-carboxylate 

Downstream Products

• 1256810-26-0 6-bromo-3-methoxypyridine-2-carboxylic acid 

Relevant articles and documents

5-AMINO-4-HYDROXY-7- (IMIDAZO [1,2-A] PYRIDIN-6- YLMETHYL)-8-METHYL-NONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION

Compounds of the general formula (I) or its salt or a compound in which one or more atoms are replaced by their stable, nonradio-active isotopes, in particular its pharmaceutically acceptable salt; in which X is -CH2-; R1 is a mono- to tetrasubstituted, mono- or bicyclic, unsaturated heterocyclic radical having 1 to 4 nitrogen atoms, R2 is C1-6alkyl or C3-6cycloalkyl; R3 is independently of one another H, C1-6alkyl, C1-6alkoxycarbonyl or C1-6alkanoyl; R4 is C2-6alkenyl, C1-6alkyl, unsubstituted or substituted aryl- C1-6alkyl or C3-8cycloalkyl; R5 is -Lm-R6; L is C1-6alkylene which is optionally substituted by 1-4 halogen, or a linker: formula (II) n = 0, 1 or 2; m = 0 or 1; R6 is a radical composed of 2 cyclic systems selected from bicyclo[x.y.z]alkyl, spiro[o.p]alkyl, mono- or bioxabicyclo[x.y.z]alkyl or mono- or bioxaspiro[o.p]alkyl, all of which may be substituted by 1-3 substituents selected from C1-6alkyl, C1-6alkoxy, cyano, halogen, C1-6alkoxy- C1-6alkyl, hydroxy-C1-6alkyl or dialkylamino, or if m = 0: is also saturated C3-8heterocyclyl which comprises 1-2 oxygen atoms, substituted by 1-3 substituents selected from C1-6alkyl, C1-6alkoxy, cyano, halogen, C1-6alkoxy- C1-6alkyl, hydroxy- C1-6alkyl or dialkylamino, or if m = 1: is also saturated C3-8heterocyclyl which comprises 1-2 oxygen atoms, optionally substituted by 1-3 substituents selected from C1-6alkyl, C1-6alkoxy, cyano, halogen, C1-6-alkoxy-C1-6alkyl, hydroxy-C1-6alkyl or dialkylamino; have renin- inhibiting properties and can be used as medicines for the treatment of hypertension.

PIPERIDINE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS

A novel piperidine derivative represented by the formula (I) (I) wherein Ar is a phenyl group optionally having substituent(s), R?1? is a hydrogen atom, a hydrocarbon group optionally having substituent(s), an acyl group or a heterocyclic group optionally having substituent(s), Z is a methylene group optionally having C?1-6#191 alkyl group(s), ring A is a piperidine ring optionally further having substituent(s), and B is a monocyclic aromatic heterocyclic group optionally having substituent(s) (substituents of monocyclic aromatic heterocycle may be bonded to each other to form a ring), or a salt thereof has a superior tachykinin receptor antagonistic action and the like, and is useful as an agent for the prophylaxis or treatment of lower urinary tract disease and the like.