945965-71-9

Upstream product

• 6082-99-1 5-iodo-2-methoxy-3-methylbenzoic acid methyl ester 
• 945965-68-4 (E)-tert-butyl 6-(4-methoxy-3-(methoxycarbamoyl)-5-methylphenyl)-6-(tributylstannyl)hex-5-enoate 
• 945965-66-2 (E)-methyl 5-(6-tert-butoxy-6-oxo-1-(tributylstannyl)hex-1-enyl)-2-methoxy-3-methylbenzoate 
• 945965-67-3 (E)-5-(6-tert-butoxy-6-oxo-1-(tributylstannyl)hex-1-enyl)-2-methoxy-3-methylbenzoic acid 
• 73448-14-3 hex-5-ynoic acid tert-butyl ester 
• 53293-00-8 hex-5-ynoic acid 
• 945965-69-5 (E)-tert-butyl 6-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-6-(4-methoxy-3-(methoxycarbamoyl)-5-methylphenyl)hex-5-enoate 
• 945965-70-8 (E)-6-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-6-(4-methoxy-3-(methoxycarbamoyl)-5-methylphenyl)hex-5-enoic acid 
• 593-56-6 N-methoxylamine hydrochloride 

Downstream Products

• 1065027-90-8 (Z)-5-((1Z,6Z)-6-bromo-1-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-6-(methoxylmino)hex-1-enyl)-N,2-dimethoxy-3-methylbenzimidoyl bromide 
• 1065027-89-5 (Z)-5-((1E,6Z)-6-bromo-1-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-6-(methoxylmino)hex-1-enyl)-N,2-dimethoxy-3-methylbenzimidoyl bromide 

Relevant academic research and scientific papers

ALKENYLDIARYLMETHANES HAVING NITROGEN-CONTAINING CARBOXYLIC ACID DERIVATIVES

Alkenydiarylmethane compounds are described. Such compounds are a class of non-nucleoside inhibitors of HIV-I reverse transcriptase, which may also be used as part of a combination therapy to treat HIV infection. Compounds described herein exhibit antivir

Synthesis and anti-HIV activity of new metabolically stable alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors incorporating N-methoxy imidoyl halide and 1,2,4-oxadiazole systems

The alkenyldiarylmethanes (ADAMs) are a unique class of non-nucleoside reverse transcriptase inhibitors (NNRTIs) that are capable of inhibiting HIV-1 reverse transcriptase (RT) through an allosteric mechanism. However, the potential usefulness of the ADAM