94598-32-0

Usage

Uses

Used in Organic Synthesis:
1-BROMO-10,12-PENTACOSADIYNE is used as a chemical intermediate for the synthesis of various organic compounds. Its reactive triple bonds allow for the formation of new chemical bonds and the creation of complex molecules.
Used in Materials Science:
1-BROMO-10,12-PENTACOSADIYNE is used as a precursor in the production of organic thin films, polymers, and liquid crystals. Its unique properties, such as its reactivity and the presence of triple bonds, contribute to the development of advanced materials with specific characteristics and applications.
Used in Research and Development:
1-BROMO-10,12-PENTACOSADIYNE is used as a research compound to study the properties and behavior of diacetylene compounds. This helps scientists and researchers to better understand the potential applications and limitations of these compounds in various industries.

InChI:InChI=1/C25H43Br/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26/h2-12,17-25H2,1H3

Upstream product

• 92266-90-5 10,12-pentacosadiyne-1-ol 
• 66990-32-7 10,12-pentacosanodiynoic acid 

Relevant academic research and scientific papers

Impact of the surface charge of polydiacetylene micelles on their interaction with human innate immune protein C1q and the complement system

Polydiacetylene (pDA) micelles have been demonstrated to be effective drug carriers for cancer therapy in mouse model. However, little is known about their interaction with the human complement system, which constitutes an important part of the innate immune system and can cause severe hypersensitivity reactions. Herein, we investigate the influence of micelle surface charge on the binding of complement protein C1q, the target recognition unit that activates the classical complement pathway and performs a range of other important physiological functions. Besides the classical pathway, we also investigate the surface charge effect on complement activities through the other activation pathways, namely, the MBL-dependent lectin pathway and the alternative pathway. We synthesized three samples of pDA micelles bearing neutral, anionic, and cationic surface charge motifs, respectively. Surface plasmon resonance showed that none of these micelles interacted with C1q. Results from serum complement activation assays indicated that all micelles were inert to complement, except for the anionic pDA micelles, which activated the alternative pathway.

Aqueous 1,3-dipolar cycloadditions promoted by copper nanoparticles in polydiacetylene micelles

A novel colloidal catalyst was developed through the encapsulation of cuprous oxide nanoparticles in polydiacetylene micelles. The Cu-based catalyst was applied to the Huisgen cycloaddition reaction in fully aqueous medium. The process neither requires he

SYNTHESIS OF SURFACE-ACTIVE LIQUID-CRYSTALLINE DIYNOIC ESTERS AND DIYNYL ETHERS

Surface-active diynoic esters and diynyl ethers exhibiting liquid-crystal characteristics were obtained by the reaction of the chlorides of diynoic acids and diynyl bromides with 4-(4-hydroxyphenylazo)nitrobenzene, 4-(4-hydroxyphenylazo)benzoic, 4-(4-hydr