945997-19-3Relevant academic research and scientific papers
Synthesis and stereochemical assignment of FR252921, a promising immunosuppressant
Falck, J. Russell,He, Anyu,Fukui, Hiroki,Tsutsui, Hideyuki,Radha, Akella
, p. 4527 - 4529 (2007)
Synthetic detective work: FR252921, an unusual 19-membered lactone-dilactam, and three of its diastereomers were prepared by a versatile, convergent strategy from three key segments (see scheme). Comparison of the synthetic compounds with natural material established conclusively that FR252921 has the configuration 12S,13R,18R.
