946075-13-4

Basic information

• Product Name: Isavuconazonium sulfate
• Synonyms: Isavuconazonium sulfate;Isavuconazon;BAL 8557-002;N-Methylglycine [2-[[[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-2-thiazolyl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-4H-1,2,4-triazolium-4-yl]ethoxy]carbonyl]methylamino]-3-pyridinyl]methyl ester sulfate (1:1);API-Antifungal Infection
• CAS NO: 946075-13-4
• Molecular Formula: C35H36F2N8O9S2
• Molecular Weight: 814.8353464
• Mol File: 946075-13-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isavuconazonium sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: Isavuconazonium sulfate(946075-13-4)
• EPA Substance Registry System: Isavuconazonium sulfate(946075-13-4)

Safety Data

• Hazardous Substances Data: 946075-13-4(Hazardous Substances Data)

Usage

Uses

Isavuconazonium Sulfate can be prepared to be used as an antifungal drug.

Definition

ChEBI: An azaheterocycle sulfate salt that is a prodrug for isavuconazole, an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.

Upstream product

• 338990-31-1 N-methyl N-(3-[((N-tert-butoxycarbonyl-N-methylamino)acetoxy)methyl]pyridin-2-yl)carbamic acid (1-chloroethyl) ester 
• 241479-67-4 Isavuconazole 
• 338990-84-4 isavuconazonium chloride 

Relevant articles and documents

Method for preparing antifungal drug isavuconazonium sulfate

The invention discloses a method for preparing isavuconazonium sulfate, and the method comprises the following steps: carrying out ion exchange on a compound shown as a formula 6 and styrene hydrogensulfate anion exchange resin in an organic solvent aqueo

Method for preparing isavuconazonium monosulfate by bisulfate/sulfate anion exchange technology

The invention discloses a method for preparing isavuconazonium monosulfate by bisulfate/sulfate anion exchange technology, the method comprises the following steps: preparing Boc-protected isavuconazonium iodized salt from formula 1 compound isavuconazole

A PROCESS FOR THE PREPARATION OF ISAVUCONAZONIUM OR ITS SALT THEREOF

The present invention relates to a process for the preparation of stable Isavuconazonium or its salt thereof. In particular of the present invention relates to process for the preparing of isavuconazonium sulfate, Isavuconazonium iodide hydrochloride and