94613-37-3Relevant articles and documents
The Synthesis od 1H-Benzimidazole Derivatives Containing a 9H-Xanthene or 9H-Thioxanthene Ring
Okabayashi, Ichizo,Fujiwara, Hidetoshi
, p. 1401 - 1402 (2007/10/02)
2-(9H-Xanthen-9-ylmethyl)-1H-benzimidazole (2a) was prepared by condensing 9H-xanthene-9-acetic acid (1a) with 1,2-benzenediamine.Similarly, 2-(9H-thioxanthen-9-ylmethyl)-1H-benzimidazole (2b) and its S,S-dioxide (2d) were obtained.Compound 2d was also prepared by oxidizing 2b with hydrogen peroxide in acetic acid.Heating of 9H-thioxanthene-9-acetic acid 10-oxide (1c) with 1,2-benzenediamine gave 9-methylene-9H-thioxanthene (3). 2-(9H-Thioxanthen-9-ylmethyl)-1H-benzimidazole S-oxide (2c) was obtained by oxidizing 2b with m-chloroperbenzoic acid in acetone.