Cas 946136-86-3,hex-5-enoic acid {2-[2-amino-6-(2-vinyl-phenyl)-4H-quinazolin-3-yl]-ethyl}-amide

946136-86-3

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Basic information

Product Name: hex-5-enoic acid {2-[2-amino-6-(2-vinyl-phenyl)-4H-quinazolin-3-yl]-ethyl}-amide
Synonyms: hex-5-enoic acid {2-[2-amino-6-(2-vinyl-phenyl)-4H-quinazolin-3-yl]-ethyl}-amide
CAS NO:946136-86-3
Molecular Formula:
Molecular Weight: 388.513
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: hex-5-enoic acid {2-[2-amino-6-(2-vinyl-phenyl)-4H-quinazolin-3-yl]-ethyl}-amide(CAS DataBase Reference)
NIST Chemistry Reference: hex-5-enoic acid {2-[2-amino-6-(2-vinyl-phenyl)-4H-quinazolin-3-yl]-ethyl}-amide(946136-86-3)
EPA Substance Registry System: hex-5-enoic acid {2-[2-amino-6-(2-vinyl-phenyl)-4H-quinazolin-3-yl]-ethyl}-amide(946136-86-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 946136-86-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 946136-86-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,1,3 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 946136-86:
(8*9)+(7*4)+(6*6)+(5*1)+(4*3)+(3*6)+(2*8)+(1*6)=193
193 % 10 = 3
So 946136-86-3 is a valid CAS Registry Number.

946136-86-3Upstream product

946136-86-3Downstream Products

946136-86-3Relevant academic research and scientific papers

MACROCYCLE DERIVATIVES USEFUL AS INHIBITORS OF beta-SECRETASE (BACE)

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Page/Page column 26, (2010/11/28)

The present invention is directed to macrocycle derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.

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