946152-80-3 Usage
Uses
Used in Pharmaceutical Industry:
(1R,3R)-3-hydroxy-cyclopentanecarboxylic acid benzyl ester is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its chiral nature and benzyl ester moiety make it a valuable precursor for the development of new drugs and active pharmaceutical ingredients.
Used in Fragrance Industry:
In the fragrance industry, (1R,3R)-3-hydroxy-cyclopentanecarboxylic acid benzyl ester is employed as a starting material for the production of various scent compounds. Its unique structure allows for the creation of novel fragrance molecules with distinct olfactory properties.
Used in Organic Synthesis:
(1R,3R)-3-hydroxy-cyclopentanecarboxylic acid benzyl ester is used as a versatile building block in organic synthesis. Its benzyl ester group and chiral centers enable the synthesis of a wide range of organic compounds, including complex molecules and biologically active substances.
Used in Asymmetric Synthesis and Catalysis:
Due to its chiral nature, (1R,3R)-3-hydroxy-cyclopentanecarboxylic acid benzyl ester has potential applications in asymmetric synthesis and catalysis. It can be employed as a chiral auxiliary or ligand in various catalytic processes, facilitating the selective formation of enantiomerically pure products.
Check Digit Verification of cas no
The CAS Registry Mumber 946152-80-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,1,5 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 946152-80:
(8*9)+(7*4)+(6*6)+(5*1)+(4*5)+(3*2)+(2*8)+(1*0)=183
183 % 10 = 3
So 946152-80-3 is a valid CAS Registry Number.
946152-80-3Relevant academic research and scientific papers
The discovery of BMS-457, a potent and selective CCR1 antagonist
Gardner, Daniel S.,Santella III, Joseph B.,Duncia, John V.,Carter, Percy H.,Dhar, T.G.Murali,Wu, Hong,Guo, Weiwei,Cavallaro, Cullen,Van Kirk, Katy,Yarde, Melissa,Briceno, Stephanie W.,Robert Grafstrom,Liu, Richard,Patel, Sima R.,Tebben, Andrew J.,Camac, Dan,Khan, Javed,Watson, Andrew,Yang, Guchen,Rose, Anne,Foster, William R.,Cvijic, Mary Ellen,Davies, Paul,Hynes Jr., John
, p. 3833 - 3840 (2013/07/25)
A series of compounds which exhibited good human CCR1 binding and functional potency was modified resulting in the discovery of a novel series of high affinity, functionally potent antagonists of the CCR1 receptor. Issues of PXR activity, ion-channel pote
