946568-11-2

Upstream product

• 842132-15-4 4-(2-bromoethoxy)-3-methoxyaniline 
• 49827-15-8 t-butyl iodoacetate 
• 2506-46-9 α-Bromo-ω-(2-methoxy-4-nitrophenoxy)ethane 
• 3251-56-7 2-methoxy-4-nitrophenol 

Downstream Products

• 946568-13-4 C₂₉H₃₉NO₉ 

Relevant academic research and scientific papers

Ferulic acid and benzothiazole dimer derivatives with high binding affinity to β-amyloid fibrils

New ferulic acid and benzothiazole dimer derivatives were synthesized and evaluated by in vitro competition assay using [125I]TZDM for their specific binding affinities to Aβ fibrils. In particular, 4a showed the most excellent binding affinity (Ki = 0.53 nM), compared to PIB (Ki = 0.77 nM), for benzothiazole binding sites of Aβ1-42 fibrils. This result suggests a possibility of a potential AD diagnostic probe for detection of Aβ fibrils.