94665-46-0Relevant academic research and scientific papers
Synthesis of chiraphos via asymmetric hydrogenation of 2,3- bis(diphenylphosphinoyl)-buta-1,3-diene
Beghetto, Valentina,Matteoli, Ugo,Scrivanti, Alberto
, p. 155 - 156 (2000)
(S,S)-2,3-Bis(diphenylphosphinoyl)butane, an immediate precursor of (S,S)-CHIRAPHOS, can be obtained with 70% de and 71% op via double asymmetric hydrogenation of 2,3-bis(diphenylphosphinoyl)buta-1,3-diene in the presence of Ru-(S)-BINAP catalysts.
NEW ENTRY TO THE PREPARATION OF CHIRAL BIS(DICYCLOHEXYLPHOSPHINO)ALKANE DERIVATIVES. USE FOR RHODIUM-CATALYZED HYDROGENATION OF CARBONYL COMPOUNDS
Yamamoto, Keiji,Saeed-Ur-Rehman
, p. 1603 - 1606 (2007/10/02)
Conversion has been achieved of two representative chiral diphosphines, (-)-DIOP and (S,S)-Chiraphos, into the corresponding bis(dicyclohexylphosphino)alkane derivatives, the latter being used for chiral ligands of the rhodium(I) catalyst in the homogeneous hydrogenation of prochiral carbonyl compounds.
