94669-69-9

Upstream product

• 538-51-2 benzylidene phenylamine 
• 94615-13-1 (5S)-1-carboxymethyl-5-<(methoxymethoxy)methyl>-2-pyrrolidinone 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 17342-08-4 (S)-Pyroglutaminol 
• 130675-41-1 (5S)-1-<(benzyloxycarbonyl))methyl>-5-<(methoxymethoxy)methyl>-2-pyrrolidinone 
• 94615-12-0 (S)-5-(methoxymethoxy)methyl-2-pyrrolidinone 

Downstream Products

• 94669-72-4 (3R,4S)-3-amino-1,4-diphenyl-2-azetidinone 
• 130675-43-3 Acetic acid 5-oxo-1-((3R,4S)-2-oxo-1,4-diphenyl-azetidin-3-yl)-pyrrolidin-2-yl ester 
• 94615-17-5 (3R,4S)-1,4-diphenyl-3-<(5S)-5-(carboxyl)pyrrolidin-2-on-1-yl>-2-azetidinone 
• 130675-44-4 (3R,4S)-1,4-diphenyl-3-<3-(methoxycarbonyl)propionamido>-2-azetidinone 
• 94615-18-6 5-Hydroxy-1-((3R,4S)-2-oxo-1,4-diphenyl-azetidin-3-yl)-pyrrolidin-2-one 
• 94615-19-7 (3R,4S)-3-(pyrrolidin-2,5-dion-1-yl)-2-azetidinone 
• 16876-72-5 (R)-2-amino-N,3-diphenyl-propanamide 
• 130675-42-2 (3R,4S)-1,4-diphenyl-3-<(5S)-5-(hydroxymethyl)pyrrolidin-2-on-1-yl>-2-azetidinone 

Relevant academic research and scientific papers

SYNTHETIC STUDIES ON OPTICALLY ACTIVE β-LACTAMS. ASYMMETRIC SYNTHESIS OF β-LACTAMS BY THE CYCLOCONDENSATION UTILIZING CHIRAL HETEROCYCLIC COMPOUNDS DERIVED FROM L-(+)-TARTARIC ACID AND (S)-GLUTAMIC ACID

Asymmetric cyclocondensation of the chiral heterocyclic compounds (2,4) with imines (5) gave either cis- or trans-β-lactams with high diastereomeric purity up to 96percent, and the optically pure phenylalanine derivative (9) was obtained from the β-lactams produced.