94670-56-1Relevant articles and documents
The Design and Development of a Potent and Selective Novel Diprolyl Derivative That Binds to the N-Domain of Angiotensin-I Converting Enzyme
Fienberg, Stephen,Cozier, Gyles E.,Acharya, K. Ravi,Chibale, Kelly,Sturrock, Edward D.
, p. 344 - 359 (2018/02/10)
Angiotensin-I converting enzyme (ACE) is a zinc metalloprotease consisting of two catalytic domains (N- and C-). Most clinical ACE inhibitor(s) (ACEi) have been shown to inhibit both domains nonselectively, resulting in adverse effects such as cough and a